2006 issue 3-4


Volume 22, issue 3-4

Case report

Efficacy of citalopram in more than maximal dose in drug-resistant depression. The treatment outcome after switching into the escitalopram. Case report

Łukasz Święcicki1
1. II Klinika Psychiatryczna Instytutu Psychiatrii i Neurologii w Warszawie
Farmakoterapia w Psychiatrii i Neurologii, 2006, 3–4, 187–190
Keywords: citalopram, escitalopram, drug-resistant depression, over-maximal dose


A case report of 30 years white man with chronic, drug-resistant depression, was presented. The condition resolved during treatment with citalopram, 100 mg/day (against medical advise). There was no side effects. Results of debryzochine test show activity of CYP2D6 to be in normal range. After switching into the escitalopram, after two years of citalopram treatment, it would be possible to change the dosing to 10 mg per day, without adversive effects on to the psychiatric status.

Address for correspondence:
Łukasz Święcicki
Instytut Psychiatrii i Neurologii
Al. Sobieskiego 9, 02-957 Warszawa
tel. (022) 45 82 522
e-mail: swiecick@ipin.edu.pl