Aim. In this report methods most commonly used in the assessment patients suffering from Multiple Sclerosis are presented.
Review. Heterogenity and changeability of symptoms are characteristic for MS. The sequele of disease is disability and lowering of quality of life. Clinimetrics should be regarded as the measurement of clinical and patient relevant phenomena. Clinimetrics is a specific domain of knowledge that focuses on the construction and evaluation of clinical indexes. It enables objective observation of the course of disease and effects of treatment. In this article Kutzke's Neurologic Impairment in MS and Extended Disability Status Scale are presented. Questionnaires most frequent used for evaluation of quality of life in MS are described. The phenomenon of fatigue in MS is also mentioned.