In the paper the treatment of spasticity with traditional pharmacological methods – injection of phenol and ethanol was discussed. Spasticity is one of most common and important problem in neurology because of the degree of spasticity may reflect the intensity of disability neurological patients with upper motor neuron injure (due to stroke, multiple sclerosis, trauma). Phenol and ethanol are the long-lasting local blocking agents used traditionally to treat of spasticity. Beside clinical advantages, the main problems with this kind of treatment are correct selection of patients, appropriate selection of involved muscles, and limitation due to unpleasant side effects (painful injections, chronic pain, and dysesthesias).
Additionally to this review the results of some clinical observation 6 patients treated with 40% ethanol were presented. In most cases improvement was observed.