2000 issue 2


Volume 16, issue 2


Placebo w badaniach leków psychotropowych

Adam Bilikiewicz1
1. II Klinika Chorób Psychicznych AM w Gdańsku
Farmakoterapia w Psychiatrii i Neurologii, 2000, 2, 114-121


On the basis of literature data and own longstanding experience, the author discusses the role of placebo in clinical evaluation of psychotropic drugs. He points out the ethical and legal aspects of the double blind, placebo controlled trials, and suggests that this procedure should be strongly limited in psychiatry. In his opinion, patients with mandatory requirements for active therapy should be excluded from placebo trials. He is also critical of the requirement for a "wash-out" period.